Cohesin’s Scc1, Smc1 and Smc3 subunits form a tripartite ring structure, and it has been proposed that cohesin holds sister DNA molecules together by trapping them inside its ring. To test this ...

Twenty years ago, the protein complex cohesin was first described by researchers. They found that its shape strikingly corresponds to its function: when a cell divides, the ring-shaped structure ...

The journal Science publishes the new findings in its current issue. The ring-shaped cohesin complex ensures that each round of cell division yields two daughter cells with identical sets of ...

"We found that cohesin's ring needs to open for certain processes, like DNA replication, to progress," says Nagoya University chromosomal biologist Tomoko Nishiyama, who led the study. Cohesin is ...

Best known for its ability to regulate the separation of sister chromatids during cell division, the cohesin protein complex, a ring-shaped structure, has shown that it has other powers ...

Cohesin is a ring-shaped protein complex involved in the spatial organization of the genome and in mitotic chromosome structure. Vertebrate somatic cells have two versions of cohesin that contain ...

Cohesin is a protein that forms a ring-shaped complex which wraps and alters the DNA molecule shape. It moves through the DNA and creates specific loops in the genetic material which determine the ...

Twenty years ago, the protein complex cohesin was first described by researchers at the IMP. They found that its shape strikingly corresponds to its function: when a cell divides, the ring-shaped ...

A good example of this is cohesin, a ring-shaped protein complex that embraces DNA to control cell division. Just a few months ago, and after several studies in the same direction, the sequencing ...

Cohesin is a ring-shaped protein that surrounds and moves around the DNA molecule, forming the loops. It is a crucial process for the cell. Understanding how cohesin works has been one of the ...

A diagram of the protein complex cohesin in its assumed ring-shaped configuration. The scissors represent the action of the enzyme Cut1, which breaks apart the molecule to release DNA. Disclaimer ...