In cleft lip and palate, the formation of the mouth region is impaired during embryonic development. To date, more than 45 genetic segments are known to contain common risk variants.

A cleft lip and palate occurs when the tissues that form these structures do not fuse properly during pregnancy. The causes of cleft lip and palate are not fully understood, but they may involve a ...

Around one in 700 babies worldwide are born with a cleft lip or palate. However, many parents and carers have little idea of how clefts affect children’s ability to make speech sounds and learn ...

Babies born with a cleft lip or cleft palate, or both, will face some additional challenges in the early years of their lives, and so will their parents. Babies with clefts need to have surgery ...

Tony Markus, consultant maxillofacial surgeon, is leader of the cleft team at Poole Hospital. he says: While there is a wide spectrum of severity of clefts of either lip, palate or both ...

The daily ordeals and struggles faced by parents of children born with cleft and palate deformities were ... by a Professor of Oral Pathology, Radiology, and Medicine, Azeez Butali, the Lagos ...