In this paradigm-changing study, researchers found that short fragments of circular DNA that encode cancer genes are far more common in cancer cells than previously believed. They showed that ...

Circular DNA, thought to be an accidental byproduct, is borrowing the cell’s DNA repair mechanisms to copy itself DURHAM, N.C. -- Like its viral cousins, a somewhat parasitic DNA sequence called a ...

But work in the past 10 years suggests those DNA tidbits, which are circular, aren’t just some cellular debris. Cancer cells use the circles to rapidly grab or shed genes linked to tumor growth ...

They exist as circular pieces of DNA in the nuclei of tumor cells outside chromosomes. Transcription of the amplified ecDNA genes can promote oncogenic processes, such as the increased expression ...

They hijack a little-known piece of the cell's DNA repair function to close ... The retrovirus HIV, which causes AIDS, is also known to form circular DNA. "I think these elements are the source ...

Extrachromosomal DNA (ecDNA) is a unique form of circular DNA that exists outside of normal chromosomes. Found exclusively in tumor cells, it often carries cancer-promoting genes (oncogenes ...

the extrachromosomal DNA (ecDNA) found in some cancer cells is not always split evenly. Lacking centromeres, these circular bits of DNA are often unevenly parceled to daughter cells. Some daughter ...

Researchers studying circular RNAs (circRNAs) in brain cells have reported new insights into neurological diseases. Investigators headed by a team at Brigham and Women’s Hospital used a laser ...

Mitochondria are often referred to as the “powerhouses” or “batteries” of a cell, due to their role in energy conversion, among other critical molecular processes. They possess their own circular DNA ...