Chronic tophaceous gout (CTG) is an independent risk factor for colorectal cancer (CRC), according to study results presented at Digestive Disease Week (DDW), held from May 6 to 9, 2023 in Chicago ...

There are only a few case reports that are published so far, indicating that there is increased production of calcitriol in patients with chronic tophaceous gout similar to the mechanism that ...

Without treatment, gout can become a chronic condition and increase your risk of developing tophi and joint damage. Asymptomatic hyperuricemia You have an abundance of uric acid in your blood ...

Tophi are firm, painless yellow lesions that form in and around the joints in people with advanced gout. They have a uric acid (monosodium urate) core, and the skin that covers them can become ...

Clinicians need systematic approaches to treatment-refractory gouty arthritis and tophaceous disease (particularly with erosive, destructive chronic arthritis), including strategies to tackle ...

in various body tissues and influence the progressive course of chronic tophaceous gout. With accumulating experience in the continuous use of uricosuric agents, a more hopeful attitude toward the ...

Most cases of gout respond to nonsurgical management. However, the condition may progress to a more severe form called chronic tophaceous gout, when uric acid crystals form masses of white growths ...

A 53-year-old man had chronic tophaceous gout of 15 years' duration. The past history was positive for active pulmonary tuberculosis at the age of 23 that subsequently became arrested. Repeated ...

Patients with confirmed tophi and more frequent acute gout attacks ... patients who reported symptoms of inadequately controlled chronic gout (similar to refractory chronic gout), defined here ...

In terms of comorbidities, 5% reported chronic kidney disease ... greater impairment of work productivity and activity. Tophaceous gout was associated with greater absenteeism and overall work ...

This is an uncommon form of gout caused by uric acid crystal deposition in the joints, tendons, and other soft tissues. Chronic tophaceous gout usually develops after a long period of time.

Allopurinol (Aloprim, Zyloprim) treats chronic gout by lowering the uric acid produced in your body. Febuxostat (Uloric) also lowers uric acid production but would be used with caution if you are ...