Chromosome territories (CTs) with different gene ... of gene regulation requires much more detailed knowledge of gene expression in the context of nuclear architecture and organization.

Chromosome territories can only form in cells that ... region that changes its nuclear position as a result of aberrant gene expression may be indicative of a disease process.

"We used to think that the chromosomes of the mosquito did not form territories ... of a mechanism connecting genome structure to gene expression.

Chromosomes occupy specific regions of the cell nucleus called chromosome territories ... and was directly related to the regulation of gene expression. “We have demonstrated that the ...

Breakthrough in sex-chromosome regulation Date: October 3, 2019 Source: Karolinska Institutet Summary: Researchers have uncovered a chromosome-wide mechanism that keeps the gene expression of sex ...

the initial step of the expression of genes on the X chromosome. However, because Xist is not a traditional protein-coding gene, until now researchers have had trouble figuring out exactly how ...

An important player in the healthy development of female embryos turns out also to play a key role in regulating the behavior of chromosome loops and gene expression in both sexes, according to a ...

Copies of the same gene can appear on different chromosomes, boosting the survivability of humans as a species. Each gene is responsible for different functions. For example, some tell cells how ...

Suppressing chromosomal DNA repair ability increased the rate of duplicate chromosome elimination. The authors show that the chromosomal rescue reversibly restores both gene expression and ...

a collaborative team of UCLA researchers have found that female mouse and human NK cells have an extra copy of an X chromosome-linked gene called UTX. UTX acts as an epigenetic regulator to boost ...