Can we predict that natural selection will weed out genetic disease over time? Sickle-cell trait haplotype distribution shows the genetic advantages of this mutation. In the deoxygenated ...

Scientists from Johns Hopkins Medicine and eight other institutions in the United States, Africa and Europe say they have ...

Scientists have found a potential new gene variant target to treat sickle cell disease, an inherited blood disorder that ...

A 21-year-old New York man who has spent much of his life battling sicken cell anemia has now been declared disease free ...

Doctors noticed that patients who had sickle cell anemia, a serious hereditary blood disease, were more likely to survive malaria, a disease which kills some 1.2 million people every year.

Scientists say they have identified a potential new gene target that could be edited to treat sickle cell disease, an ...

Why is knowing the atomic structure of molecules useful? Learn why, and how information like this about protein structure is shared through a publicly available database.

Cycles of infectious disease prevalence and virulence often reflect natural selection. Sickle Cell disease is an autosomal recessive disorder that causes anemia, joint pain, a swollen spleen ...

Scientists have discovered more than a dozen genes that regulate the production of fetal hemoglobin in people of African ...

A bone marrow transplant process co-developed by investigators at the Johns Hopkins Kimmel Cancer Center is safe and curative for adults with sickle cell disease, according to results of a trial ...