Large-scale chromosome structure and spatial nuclear arrangement have been linked to control of gene expression and DNA replication and repair. Genomic techniques based on chromosome conformation ...

DNA-binding proteins are central regulators of chromosome organization; however, in genome-reduced bacteria their diversity is largely diminished. Whether the chromosomes of such bacteria adopt ...

For decades, the Y chromosome — one of the two human sex chromosomes — has been notoriously challenging for the genomics community to sequence due to the complexity of its structure. Now, this elusive ...

The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the ...

Superman syndrome, also known as 47, XYY, is a condition classified as a chromosomal aneuploidy (which is an abnormality in chromosome structure and/or number) in which males have an additional Y ...

Changes in chromosome structure in any individual cell are probably of no importance. That one cell won't function well and might die soon. Translocations are important when they occur in a large ...

These motors play distinct roles in manipulating chromosome structure. Swimming motors, similar to RNA polymerases—enzymes ...

Get Instant Summarized Text (Gist) A new AI tool accurately predicts the 3D structure of chromosomes in individual cells, overcoming challenges of noisy and incomplete single-cell data.

Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During mitosis, centromeres serve as assembly sites for complex protein ...

This research provides a deeper understanding of how motorized processes shape chromosome structures and influence cellular functions." Peter Wolynes, study co-author and the D.R. Bullard-Welch ...