Interestingly, histone H1 is very important in stabilizing ... the packing ratio of DNA in metaphase chromosomes is approximately 10,000:1 (depending on the chromosome). This can be thought ...

DNA methylation and histone modification influence each other during development. Histone methylation can help to direct DNA methylation patterns, and DNA methylation seems to serve as a template ...

To convert a piece of cloned DNA into a centromere-containing human artificial chromosome (HAC), an array of repeated LacO sequences is incorporated ... The fusion protein binds to the LacO domains (1 ...

The histone, in turn, forms large loops. So the DNA is much, much longer than the chromosome it makes up. The DNA of one of a fruit fly's chromosomes, for example, would be 12 times longer than ...

Epigenetic modifications, such as DNA methylation and histone modifications, can affect gene expression by altering the accessibility ... The principles of inheritance were first described by Gregor ...

Chances are you've seen an illustration of DNA's double-helix structure and even pictures of the chromosomes that make up the human genome. But where and how does the famous double helix fit into ...

The DNA coils into structures called chromosomes. The chromosomes are found in the nucleus of each cell. Figure caption, Each cell with a nucleus contains chromosomes, which are made from DNA ...

They have the potential to be “incredibly useful for genome engineering, especially in cases where you want to put in a very large piece of DNA ... chromosomes, artificial ones need centromeres to ...

The ongoing major projects in the laboratory focus on the structural biology of CRISPR-Cas surveillance complexes and their suppression by anti-CRISPR proteins (in collaboration with Luciano ...