The chromosome findings in 1084 patients studied ... One (Case 13) was normal each time, and 5 others (Cases 1, 2, 3, 6 and 11) were abnormal on each occasion. The percentage of cells with breaks ...

A chromosomal abnormality occurs when there is an incorrect number of chromosomes, an incorrect amount of DNA within a chromosome, or chromosomes that are structurally flawed. These abnormalities ...

An example of a balanced structural change is the Philadelphia chromosome translocation previously described. In that case, although genetic information was rearranged into an abnormal gene ...

Hassold T, Chiu D . Maternal age-specific rates of numerical chromosome abnormalities with special reference to trisomy. Hum Genet 1985; 70: 11–17. Lin CC, De Braekeleer M, Jamro H . Cytogenetic ...

Microarray analysis identifies more chromosome abnormalities than traditional karyotyping in prenatal testing. Microarrays will also identify findings of unclear clinical significance that should ...

[44] Combining a limited karyotype with the more objective microarray data will allow for a clearer interpretation for any disease-causing chromosome abnormalities, if any, in the fetus undergoing ...