More information: Liangliang Yang et al, Enantioselective type II intramolecular [5 + 2] cycloadditions of oxidopyrylium ylides using chiral-phosphoric-acid catalysis, Nature Synthesis (2025). DOI ...

carbon -- in presence of chiral imidazoline phosphoric acid catalysts, and obtained yields as high as 99% with a maximum enantiopurity of 96%. "Our study presents the first highly stereoselective ...

On the other hand, the adverse effects of phosphoric acid on human health are impeding market expansion. But, both the commercialization of chiral phosphoric acid as a catalyst and the extraction ...

groups on the α-carbon--in presence of chiral imidazoline phosphoric acid catalysts, and obtained yields as high as 99% with a maximum enantiopurity of 96%. Our study presents the first highly ...

was obtained when tryptamine was combined with alkyl 2-oxopentanoates containing an ethyl group in the presence of a chiral phosphoric acid catalyst with imidazoline groups (chiral bis ...

“We saw a more straightforward way to do that,” Zuo says—with a single titanium catalyst that can play two different mechanistic roles, bound to a chiral phosphoric acid ligand. Light ...

Remarkably, chiral phosphoric acids (CPAs) derived from the SPHENOL backbone, developed in their own laboratories, proved to be particularly effective in inducing enantioselectivity.