Enzymes play an important role in organic synthesis thanks to their high ... can catalyze reductive amination reactions to produce chiral amines, however, transformation of bulky amines has ...

This module explores the synthesis of amines with a focus on the reductive amination reaction. Numerous examples from the discovery and commercial manufacturing of pharmaceuticals are included. After ...

New methods for absolute asymmetric synthesis using circularly polarized light ... This agent directly determines the absolute configuration of chiral amines and alcohols without any additional ...

Kaidi Li: Over centuries, chemists have utilised chiral amines for the development of biologically active small molecules and the synthesis of chiral ligands, necessitating a general and efficient ...

The discovery of new methods in synthesis is crucial to expand the range of novel compounds ... We have found that 2-lithiopyrrolidines, piperidines and other cyclic amines undergo dynamic resolution ...

In one area, we are developing alkyl alcohol and amine derivatives as cross-coupling ... reactions of cationic intermediates using chiral transition metal catalysts. These reactions deliver valuable ...