Characteristics of CNVs A change in copy number requires a change in chromosome structure, joining two formerly separated DNA sequences. These junctions give important insights into how the ...

Chromosome instability — large-scale changes in chromosome structure and number — is one of the hallmarks of cancer. But the significance of this instability is controversial — is it a cause ...

The epigenetic state of chromatin, gene activity, and chromosomal positions are interrelated. A research team from the IPK Leibniz Institute (IPK) and the Karlsruhe Institute of Technology (KIT) ...

The epigenetic state of chromatin, gene activity, and chromosomal positions are interrelated. A research team from the IPK ...

However, changes in the genome do occur ... can affect the structure of one or more chromosomes - these are chromosome structure mutations.

Results prove that inversions can be generated in plants without causing further unwanted changes in the expression of genetic information.