These data provide an important caveat for those using Lifeact and studying actin dynamics during cell stress and indicate that Lifeact may not be a universal tool for studying actin dynamics in ...
A thermal stability-based proteomic analysis identifies cytoplasmic PEBP1 as a mediator of mitochondrial dysfunction-induced stress response, highlighting its potential role in cellular adaptation ...
However, Tan and his team wanted to identify other transcription factors regulated by STING. On screening human cells to identify proteins that shuttled from the cytosol to the nucleus during STING ...
This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...