These most often wind up controlling an event in the cell nucleus. The checks and balances of these signal transduction pathways can be thought of as overlapping networks of interacting molecules ...

Cellular reprogramming is an intrinsic evolutionary trait to constantly promote adaptations that confer survival advantage. It is also more frequent during development when organs are being formed and ...

A study in mice reveals key interactions between proteins involved in fibroblast growth factor signaling and how they contribute to distinct stages of eye lens development.

The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are ...

Rutgers Health researchers have discovered that networks of misplaced immune cells drive an aggressive lung disease, ...

Ten years of substantial work by Université de Montréal immunologist Nathalie Labrecque's team at the Montreal Clinical ...

Delve into the kinase inhibitors' diverse landscape, from cancer breakthroughs to autoimmune disease innovations.

Noncanonical signaling involves interactions with other pathways without RBPJ involvement. The NOTCH pathway contributes to ...

This important study provides solid evidence that glucosylceramide synthase (GlcT), a rate-limiting enzyme for glycosphingolipid (GSL) production, plays a role in the differentiation of intestinal ...

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