Cell signalling is the mechanism by which stimuli are transmitted via a signalling cascade to effector molecules that orchestrate the appropriate response. Types of cell signalling pathways ...

The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are ...

Frizzled (Fz)/planar cell polarity (PCP) signalling is a conserved mechanism regulating the polarity of cells along the axes of a tissue. Fz/PCP regulates a diverse array of processes including ...

Coordinated development requires that cells communicate with each other. This is made possible by molecular mechanisms of cell-cell signaling, by which cells can influence each other’s fate and ...

Ten years of substantial work by Université de Montréal immunologist Nathalie Labrecque's team at the Montreal Clinical ...

The Wingless (Wg) signaling pathway is known to be responsible for one of these constrictions, but until now the underlying mechanism regulating this was not known. "We knew that Wingless participates ...

A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...