Receptors are generally transmembrane proteins, which bind to signaling molecules outside the cell and subsequently transmit the signal through a sequence of molecular switches to internal ...

Virtually every type of cell (other than red blood cells) produces one or more of these signaling molecules. Their very short half-lives means that they are very effective at signaling nearby ...

In the new study, Labrecque's team demonstrated that NOTCH signaling is involved from the very start of the CD8 + T cell differentiation period, which lasts around seven to 10 days. To the ...