New work shows that activation of the Ras guanine nucleotide exchange factor SOS is dependent upon the membrane density of phosphatidylinositol-4,5-bisphosphate (PIP 2) and GTP-bound Ras.

Membrane biophysics is the study of the physical ... and the effect they have on paracellular transport and phenomena relating to cell shape. Cell membranes are dynamic entities that are actively ...