A growing body of work suggests that cell metabolism — the chemical reactions that provide energy and building materials — ...

ID GSE266025. The asymmetric expression of HSPA2 in blastomeres governs the first embryonic cell-fate decision. ID PXD052193. differentially expressed proteins (DEPs) at the blastocyst stage in the ...

Our most recent work is focused on elucidating how a protein kinase (PINK1) controls the activity of a ubiquitin E3 ligase (Parkin) to specify cell fate decisions. Mutations in genes encoding for ...

Researchers at the Kennedy Institute have developed a new computational framework that allows simultaneous analysis of gene ...

This important study provides solid evidence that glucosylceramide synthase (GlcT), a rate-limiting enzyme for glycosphingolipid (GSL) production, plays a role in the differentiation of intestinal ...

The Choi Lab develops new synthetic biology tools to study cell-fate decisions in development. During development, cells differentiate into various cell types with distinct functions. To understand ...

Despite the importance of cell extrusion in development and aging, as well as its pathological importance in cancer progression, the cues which determine the fate of an extruded cell were ...

Sister cells are a pair of cells that share the same mother cell. In a new study published in Developmental Cell, researchers led by Université de Montréal (UdeM) professor Greg FitzHarris show ...