Their function is to replenish all of the types of (differentiated ... into any of the types of cell of the same tissue type. For example, blood stem cells found in bone marrow can differentiate ...
The ability to self-renew is an essential feature of progenitor cells and is usually lost on differentiation. However, Aziz et al. now report that the deletion of two transcription factors linked ...
Blood stem cells (hematopoietic cells ... chromosomal clocks and prevents the timed death suffered by most differentiated cells. This resetting allows the cells to be cultured indefinitely ...
“Poorly differentiated” refers to cancer cells that have more abnormalities and look less like normal cancer cells ... The only way to diagnose cancerous Hurthle cells is by surgically removing the ...
All blood cells are derived from special cells called hematopoietic stem cells (HSCs), whose differentiated progeny normally repopulate the blood. Clonal hematopoiesis develops when a single HSC ...
are the precursors of all cells of the peripheral blood, and they usually reside in a quiescent state in the bone marrow. We discovered that interferon gamma (IFNγ) promotes hematopoietic stem cell ...