The cell cycle has been the subject of intense investigation during two periods since Virchow's 1855 realization that cells only arise from pre-existing cells. At the turn of the century ...

Scientists have identified a new variant of the cell cycle that could provide insight into how diseases like cancer occur. Maggie Chen is a scientist and science journalist covering health, biology, ...

Cell cycle transitions in eukaryotes are driven by cyclin-dependent kinases (for example, Cdk1 and Cdk2), which are regulated by the availability of their cyclin partners (for example, CycA and ...

Harvest cells, want good single cell suspension Count cells Dispense aliquots of 1 million cells into labeled tubes Add 5 ml PBS and centrifuge for 5 min at 400 x g. Re-suspend cell pellet in 300 ul ...

Before a cell can divide, it must grow and make copies of all the organelles such as mitochondria and ribosomes. The cell must also replicate the chromosomes in the nucleus, then it can divide by ...

A patient with HPV-positive head and neck squamous cell carcinoma was dosed in a phase 1 clinical trial evaluating APR-1051.

When looking at cells with a microscope, the length of different stages of the cell cycle can be estimated using the formula: \(\text{Length of time in phase}=\) \(\frac{\text{observed number of ...

New research offers unprecedented insight into how an enigmatic enzyme, known as CDK7, drives the cell cycle and cell proliferation.

The cell cycle is understood to be the stages through which a cell progresses to ultimately divide into separate cells. It is this process that underlies the proliferation of life -; and is ...

The Flow Cytometry and Cell Separation Facility provides advanced cell sorting and cell analysis techniques including immunofluorescence detection of 18 colors, cell-cycle distribution, apoptosis ...

Using an unbiased approach, this important study discovered a role of Ezh2 in the differentiation of granule neuron precursors, the cell of origin for Shh group of medulloblastoma. Furthermore, the ...