为解决急性肾损伤（AKI）机制不明及治疗策略缺乏的问题，南方医科大学研究人员探究 CD44 在 AKI 中的作用。结果发现 CD44 可加重 AKI，抑制它或成治疗新策略。推荐科研读者阅读，以了解 AKI 新机制与潜在疗法。 在当今社会，急性肾损伤（AKI）就像一个隐藏在 ...

近日，南通大学的研究人员在探究CD44蛋白时意外地发现，缺失CD44的小鼠即使在高脂饮食下仍能保持苗条，而对照组小鼠则会发展为肥胖。 CD44是一种跨膜蛋白，在将细胞外刺激转化为细胞内信号级联反应中发挥重要作用，尤其是在癌细胞中。最近的研究表明 ...

Surprising findings from a study in The American Journal of Pathology show that mice with a CD44 protein deficiency stay lean, despite being on a high-fat diet Researchers investigating the role of ...

Researchers investigating the role of the protein CD44 in obesity and metabolic health found that CD44-deficient mice stayed lean even on a high-fat diet, while the control mice developed obesity.

Blocking a protein called CD44 has been shown to protect against obesity in mice on a high-fat diet, specifically by suppressing the formation of white fat cells.