为预测高级别胶质瘤（HGG）患者 CD44 表达并评估其预后意义，研究构建影像组学模型，效果良好。 高级别胶质瘤（High-grade glioma，HGG）是中枢神经系统中常见的原发性恶性肿瘤，尽管在手术、化疗、放疗和靶向治疗等方面取得了进展，但由于治疗效果有限 ...

为解决急性肾损伤（AKI）机制不明及治疗策略缺乏的问题，南方医科大学研究人员探究 CD44 在 AKI 中的作用。结果发现 CD44 可加重 AKI，抑制它或成治疗新策略。推荐科研读者阅读，以了解 AKI 新机制与潜在疗法。 在当今社会，急性肾损伤（AKI）就像一个隐藏在 ...

近日，来自河南工业大学的研究者们在Nature Communications杂志上发表了题为“CD44 connects autophagy decline and ageing in the vascular endothelium”的文章，该研究 ...

近日，来自徐州医科大学附属医院的研究者们在Cell Death and Disease杂志上发表了题为“Long noncoding RNA LINC01594 inhibits the CELF6-mediated splicing of oncogenic CD44 ...

CD44 is a glycoprotein found on the surface ... participated in these phenomena by allowing iron to enter cells through endocytosis. Scientists at the Laboratoire Chimie et Biologie du Cancer ...

15). A large fraction of fluid phase is also internalized by clathrin-independent endocytosis (reviewed in refs 2, 4). CD44, cholera toxin and fluid-phase markers were mapped to early ...

During the transition to this state, the protein CD44 takes over from transferrin and its TfR1 receptor and ensures the majority of the iron endocytosis. This leads to a significant increase in ...

Researchers investigating the role of the protein CD44 in obesity and metabolic health found that CD44-deficient mice stayed lean even on a high-fat diet, while the control mice developed obesity.

There is an elevated amounts of iron in persister cancer cells. In these cells, iron is taken up preferentially by CD44-mediated endocytosis, where iron binds to hyaluronic acid and this glycan ...

Elevated salivary levels of CD44 and total protein (TP) can identify head and neck cancer patients with an increased risk for cancer recurrence, according to a study published online Aug.