The targeting vector was linearized by SfiI digestion (New England Biolabs), precipitated by phenol/chloroform and electroporated into PRX-B6N C57BL/6N embryonic stem (ES) cells. Screening for ...

Glioblastoma (GBM) is the most aggressive and lethal form of brain cancer, with a median survival of only 15 months despite ...

Investigators have discovered a new way the cell surface protein, CD44, helps specific T helper cells develop immunologic memory. Investigators at Sanford-Burnham Medical Research Institute ...

One of the main obstacles to successfully treating breast cancer is the cells' ability to change in ways that make them resistant to treatment. Understanding the cellular mechanisms that mediate ...

Dendritic cells are divided into Type 1 (DC1) and Type 2 (DC2) dendritic cells. Each type fulfills different functions: DC1 provide an immune response to bacteria and viruses, DC2 protect against ...

As part of the immune system, dendritic cells are essential for fighting body cells that have degenerated or are infected with a virus. They trigger an immune response by presenting protein ...