Thus, cell apoptosis can be monitored by AnnexinV and 7AAD staining. Herein, we report that both intrinsic and extrinsic apoptotic pathways lead to the formation of MEACs in a caspase-3-associated ...

Thymocyte and splenocyte apoptosis were also significantly decreased in septic caspase-3 −/− mice, which indicated that caspase-3 is a key component of the sepsis lymphocyte cell death program.

In conclusion, Tim-3 was characterized as a novel immune checkpoint molecule with pathophysiological significance in respiratory oncology. Its stage-dependent expression dynamics and multimodal ...

Scientists use cell death, whether by apoptosis or necrosis, to evaluate the toxicity or effectiveness of substances of interest, including potential therapeutic agents. For example, researchers will ...