Although clinically important cardiotoxicity appears to be limited to only a few currently marketed agents, a big concern is the large number of drugs in development, many of which are multi ...

However, there are no data comparing treatment outcomes after these distinct presentations of cardiotoxicity. The primary objectives of this study were to (1) describe the incidence of cardiotoxicity ...

Moleculin Biotech reported positive topline efficacy results from its completed U.S. Phase 1B/2 clinical trial of Annamycin for treating soft tissue sarcoma lung ...

Survival benefits of fluoropyrimidine chemotherapy significantly outweighed the risks for cardiovascular events for patients ...

Trastuzumab-mediated cardiotoxicity was originally described in women with metastatic breast cancer. The incidence rates were 13% when the antibody was administered in combination with paclitaxel ...

1 Cardiotoxicity associated with the administration of doxorubicin is most commonly manifested by dose-dependent chronic cardiomyopathy, and acute effects, including left ventricular failure ...

The use of doxorubicin is associated with, and often limited by, a risk of cardiotoxicity manifested by left ventricular dysfunction. Multiple risk factors for doxorubicin-associated cardiotoxicity ...

Individual anthracycline dose Higher individual anthracycline doses are associated with increased late cardiotoxicity, even when cumulative doses are limited [54,60] Type of anthracycline ...

Cardiotoxicity, however, is an important adverse effect that is observed with the use of this agent. Particularly with concurrent anthracycline treatment, the incidence of cardiotoxicity increases ...

These results are in line with a previous study that also looked at using lisinopril or carvedilol and showed both could help improve cardiotoxicity-free survival among anthracycline-treated ...

I haltingly explained that I had received radiation to the chest and chemotherapy that had included Adriamycin (doxorubicin, a chemotherapy drug that can cause heart muscle damage) about 16 years ...