Representative compounds were added to cardiomyocytes in a 1:3 dilution series to determine IC50 values. As before, cardiomyocyte contractions were visualized using the EarlyTox Cardiotoxicity dye ...

More information: Paula Ortiz-Sánchez et al, Loss of SRSF3 in Cardiomyocytes Leads to Decapping of Contraction-Related mRNAs and Severe Systolic Dysfunction, Circulation Research (2019).

Reumers and her colleagues have taken specific types of cells, known as cardiomyocytes, from young rats. In tandem with pacemaker cells, these begin to contract spontaneously, generating a heartbeat ...

If we look at the tissue level, different things can happen to the cardiomyocytes depending on the actual state of their environment. If you imagine that you have your cell in a very soft substrate ...

An international team of researchers has discovered how cholesterol can disrupt the internal functioning of the heart by ...

Initially, Taylor’s team reseeded the matrix with neonatal rat cardiomyocytes. In just a few days, the cells transformed into a system capable of contractions. The results were really striking. Around ...