It is the presence of cardiomyocytes that results in the early beating of the heart. Cardiomyocytes, or cardiac muscle cells are the main type of heart cells and act as the motor unit to drive heart ...

But in the adult heart, "cardiomyocytes barely divide ... severely impairing heart contraction. To investigate the mechanism through which SRSF3 supports heart contraction, the team compared ...

More information: Paula Ortiz-Sánchez et al, Loss of SRSF3 in Cardiomyocytes Leads to Decapping of Contraction-Related mRNAs and Severe Systolic Dysfunction, Circulation Research (2019).

Representative compounds were added to cardiomyocytes in a 1:3 dilution series to determine IC50 values. As before, cardiomyocyte contractions were visualized using the EarlyTox Cardiotoxicity dye ...

An international team of researchers has discovered how cholesterol can disrupt the internal functioning of the heart by ...

If we look at the tissue level, different things can happen to the cardiomyocytes depending on the actual state of their environment. If you imagine that you have your cell in a very soft substrate ...

Initially, Taylor’s team reseeded the matrix with neonatal rat cardiomyocytes. In just a few days, the cells transformed into a system capable of contractions. The results were really striking. Around ...

Reumers and her colleagues have taken specific types of cells, known as cardiomyocytes, from young rats. In tandem with pacemaker cells, these begin to contract spontaneously, generating a heartbeat ...

The importance of redifferentiation: Proteins responsible for heart muscle contraction (green ... focused on genetically engineered mice whose cardiomyocytes – the cells that make up the ...