With these preliminary findings that it is in principle possible to control dedifferentiation and thus the division of cardiac muscle cells, the scientists investigated whether repair processes could ...

Since mammals cannot regenerate cardiac muscle cells on their own, heart transplants are currently the only clinically viable option for patients suffering (or likely to suffer) heart failure.

We therefore hoped to trigger changes in gene activities by reprogramming energy metabolism to turn cell division ability back on in cardiac muscle cells." In further studies, the scientists were able ...

Coaxing the heart into making replacement cardiac muscle cells. ScienceDaily . Retrieved May 23, 2025 from www.sciencedaily.com / releases / 2011 / 12 / 111222133324.htm ...

This model system, due to its multicellularity ... "We differentiate induced pluripotent stem cells into cardiac muscle cells, fibroblasts and endothelial cells. Then we mix them with mesenchymal ...

Grafts of human cardiac muscle cells, grown from embryonic stem cells ... of arrhythmias (irregular heart rhythms) in a guinea pig model of myocardial infarction (commonly known as a heart ...

Heart failure, a leading cause of death in industrialized nations, is caused by damage to or loss of contracting cardiac muscle cells known as ... of FSTL1 in a porcine model of myocardial ...

These one-milliliter vials also contain cell culture media and additives to help keep the cardiac muscle cells alive for ... and to use microgravity as a model of human aging," says researcher ...