Another active area of research in the laboratory focuses on unraveling the mechanisms behind maladaptive, or pathological, and adaptive, or physiological, cardiac hypertrophy. In response to certain ...

Aim Differentiating physiological cardiac hypertrophy from pathology is challenging when the athlete presents with extreme anthropometry. While upper normal limits exist for maximal left ventricular ...

You have full access to this article via your institution. Though activation of the calcineurin pathway can produce cardiac hypertrophy in transgenic mice 3, the results of our study indicate that ...

One of its hallmarks is the overgrowth of cells that thicken the heart muscle and prevent the organ from pumping blood as it ...

Scientists from the University of Virginia (UVA) have developed LogiRx, a tool to expedite the development of treatments for ...

However, there are other ways hypertrophy can improve one's overall health outside of sports, including: Cardiac hypertrophy: ...

Imagine receiving a diagnosis that changes your life in an instant: hypertrophic cardiomyopathy, a heart condition that can strike without warning, claiming thousands of lives annually .

Studies conducted in human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) compared various cassette configurations and informed the final design of TN-201, which incorporates a ...

Tenaya Therapeutics (TNYA) announced the publications of positive preclinical data for TN-201, the company’s gene therapy candidate for ...

Despite having cardiovascular risk factors, asymptomatic aircraft pilots referred for medical screenings demonstrate favorable long-term outcomes and a low risk for major cardiac events.