wound repair and cancer invasion. In such migration, cells move as sheets, strands, clusters or ducts rather than individually, and use similar actin- and myosin-mediated protrusions and guidance ...

including cancer and cardiovascular disease. Cell migration begins with protrusion of the cell membrane, followed by the formation of new adhesions at the cell front that link the actin ...

In this manuscript the authors established a novel three-dimensional culture system for stratified epithelia that allows epithelial cells to undergo epithelial-to-mesenchymal transition (EMT) and ...

The changes that cancer cells undergo to metastasize are not yet fully understood. Rho (Ras-homologous) GTPases apparently play an important role. These proteins process signals within cells and ...

Efficient cell migration is driven by a process known as actin polymerization in which the building blocks of the polymer actin join together to form filaments. Now, a team led by Li-Kun Phng of ...