Disrupting the SETD2-HTT-HIP1R association inhibited actin methylation, caused defects in actin dynamics and impaired cell migration, an important function of cancer cells. Related Stories ...

Understanding The Migration Of Cancer Cells Date: June 24, 2008 Source: Goethe University Frankfurt Summary: Lamellipodia and filopodia are dynamic surface extensions of the cell which play a ...

Lamellipodia and filopodia are dynamic surface extensions of the cell which play a pivotal role in cell migration, invasion and wound healing. Biochemists from Frankfurt University have succeeded ...

Using EMT cancer cells to drive epithelial cancer cell migration and guide tumor spheroid disaggregation Jun 15, 2022 Cancer cells behave like Goldilocks: Resolving the mystery of cancer cell steering ...

A dendritic meshwork of short and highly branched actin filaments might constitute their main structural component. ... Understanding the migration of cancer cells (2008, ...

This abolished the actin response and made previously resistant cancer cells remarkably more susceptible to NK cell attack. Thus the actin response is linked to the protection of cancer cells ...

Accumulation of actin filaments (in green) at the immunological synapse of a resistant cancer cell in contact with an NK cell (in red). Cell nuclei are shown in blue. view more Credit: LIH ...

The work is published in Nature, in the paper, “Extracellular fluid viscosity enhances cell migration and cancer dissemination. “This is really the first time that the viscosity of the ...

Counterintuitively, cells move faster in thicker fluids. New research on breast cancer cells explains why, and reveals the role that fluid viscosity plays in metastasis.

The dynamics of the actin-network enable the locomotion of cells, for example during development or wound closure, but also that of spreading cancer cells. Actin also plays a role in the transport ...