and to calcium ionophores and phorbol esters, which in combination elicited a full 'T cell–activation' response but individually could be used to distinguish signaling pathways activated by ...

Using a calcium indicator, the team uncovered novel cellular behaviors tied to electrical signaling, shedding light on how early multicellular organisms sensed and responded to environmental stimuli.

Mitochondria play a crucial role in maintaining energy balance and cellular health. Recent studies have shown that chronic stress in neuronal mitochondria can have far-reaching effects, not only ...

McGill University researchers have demonstrated that AMPA receptors (AMPARs), which mediate fast excitatory neurotransmission ...

The Wingless (Wg) signaling pathway is known to be responsible for one of these constrictions, but until now the underlying ...

which was facilitated by an increase in intracellular calcium concentration induced by the binding of extracellular vesicles to the target cells.” This process where a cell secretes a protein that ...

It has long been thought that only nerve and heart cells use electric impulses to communicate, while epithelial cells — which ...

Abouleisa and her colleagues' research highlights the importance of targeting calcium signaling pathways to unlock the regenerative potential of the heart and opens new avenues for developing ...