SAN DIEGO - Neurocrine Biosciences, Inc. (NASDAQ:NBIX) has sponsored a supplement in The Journal of Clinical Endocrinology & Metabolism (JCEM) focusing on classic congenital adrenal hyperplasia (CAH), ...

In CAH, the absence of a critical enzyme allows a 46,XX fetus to produce androgens, resulting in ambiguous external genitals. A CAH individual may have an oversized clitoris and fused labia.

Congenital adrenal hyperplasia (CAH) is a genetic disorder that affects the adrenal glands, leading to hormonal imbalances due to enzyme deficiencies. The most common form of CAH is caused by a ...

Crenessity (crinecerfont) is cleared as a daily oral therapy for use in patients aged four and over with classic CAH, a disease caused by a deficiency in an enzyme that stimulates the adrenal ...

P450 oxidoreductase deficiency (PORD) is a rare genetic disorder caused by mutations in the POR gene, which encodes the cytochrome P450 oxidoreductase enzyme. This enzyme plays a crucial role in ...