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对乙酰氨基酚(APAP)致肝毒性及血小板聚集的机制新探
研究人员探究 APAP 诱导的血小板聚集及 CYP2E1 的作用,发现其影响机制,增进相关理解。 对乙酰氨基酚(Acetaminophen,APAP)过量服用仍是导致肝损伤的常见原因,主要是由于其有毒代谢产物 N - 乙酰 - 对 - 苯醌亚胺(N - acetyl - p - benzoquinone imine,NAPQI)。本研究 ...
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