Now, Bernhagen and colleagues, writing in Nature Medicine, have identified MIF as a ligand for the CXC-chemokine receptors CXCR2 and CXCR4, and suggest that targeting MIF could be used as an ...

Gao. The editorial highlights several strategies for targeting IL-8 signaling. These include therapeutic antibodies like ABX-IL-8 and HuMax-IL-8 (BMS-986253), CXCR1/CXCR2 inhibitors, and p38 MAPK ...