nlrp3激活通过cxcr2信号通路破坏血脑屏障并促进中性粒细胞浸润的机制研究及其在实验性自身免疫性脑脊髓炎中的意义 《Journal of Neuroinflammation》：NLRP3 activation induces BBB disruption and neutrophil infiltration via CXCR2 signaling in the mouse brain ...

靶向CXCR2的纳米工程策略打破胰腺癌中髓系抑制细胞的免疫耐受信号并重振抗肿瘤免疫 《Cancer Immunology, Immunotherapy》：Cell-specific nanoengineering strategy to disrupt tolerogenic signaling from myeloid-derived suppressor cells and ...

虽然已知cxcr2趋化因子受体在肿瘤生长和治疗反应中发挥关键作用，但在诱导肿瘤形成过程中cxcr2在肿瘤前体细胞中的表达之间尚未建立直接联系。

Huang说，“由于CXCR2在各个阶段的前列腺癌中都被神经内分泌细胞广泛表达，因此靶向CXCR2可能特别有益于那些所患的前列腺癌是晚期的、复发的和对 ...

Yamamoto Y, Sugimoto A, Maruo K, et al. CXCR2 signaling might have a tumor-suppressive role in patients with cholangiocarcinoma. PLoS One. Published online April 4, ...

CXCR2 Structure: Using cryogenic-electron microscopy (cryo-EM), the research team has mapped the structure of CXCR2, revealing how it interacts with various chemokines. These findings could serve ...

The expression of CXCL7 is associated with the invasive phenotype through interaction with the CXCL7/CXCR2 axis and ... -transfected cells with invasive phenotype express genes associated with the EMT ...

Eltrekibart (LY3041658, Eli Lilly) is a humanized monoclonal antibody that binds to the seven ligands that signal through CXCR1 and CXCR2, according to Seth Forman, MD, ...

Conclusions. The study showed that, in addition to CYFRA 21-1, the determination of the percentages of lymphocytes with CXCR1 and the percentages of monocytes with CXCR2 in the blood population of ...