The most common biomarkers of brain injury after CA are neuron-specific enolase (NSE) and S100B, which are commonly released into the cerebrospinal fluid (CSF) and then the systemic circulation ...

Because cognitive loss correlates with damage to synapses, synaptic markers might do a better job of tracking clinical outcomes. However, these proteins occur in very low levels in cerebrospinal fluid ...

That may be about to change. The Food and Drug Administration issued its first approval for a fluid biomarker test May 4, greenlighting Fujirebio’s Lumipulse G cerebrospinal fluid Aβ42/40 assay. This ...

Axonal neurodegeneration leads to formation of neurofilaments which first accumulate in CSF of ALS patients, and then slowly these neurofilaments enter blood circulation. Owing to rapid ...