点击蓝字关注我们【导读】汇集光学筛选可以研究大规模的细胞相互作用、形态学或动力学，但它们尚未利用高度复杂的单细胞分辨转录组读数的力量为分子通路提供信息。2025年3月12日，美国麻省理工学院/哈佛大学的研究团队在期刊《Cell》上发表了题为“Simu ...

Human extracellular matrices can be edited in their composition using the CRISPR/Cas9 system, leading to materials exhibiting tailored regenerative capacities.

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into ...

本研究利用CRISPR激活（CRISPRa）技术，成功构建了模拟小鼠胚胎早期发育的三维模型（CPEMs），揭示了其在胚胎形态发生中的关键作用，为胚胎发育研究提供了新工具。 本研究聚焦于利用CRISPR激活（CRISPRa）技术构建小鼠胚胎模型（CPEMs），模拟胚胎早期发育过程 ...

This study provides a potentially useful investigation into the positive role of BDNF/TrkB signaling in implanted dental pulp stem cells to enhance dentin regeneration in the context of dental caries.

Tel Aviv University scientists say that they can inject CRISPR genetic 'molecular scissors' to shrink tumors by 90%; ...

Over the past 15 years, developments in the gene-editing technique known as CRISPR-Cas9 have produced significant new ...

Targeted CRISPR lipid nanoparticles eliminated 50% of tumors in mice with head and neck cancer.

"These cells co-develop together, just like they would in an actual embryo, and establish that history of being neighbors," ...

Researchers from Tel Aviv University utilized CRISPR to cut a single gene from cancer cells of head and neck tumors—and successfully eliminated 50% of the tumors in model animals. This study was ...