In about a third of patients, the gene for dystrophin has small deletions or single base mutations that render it nonfunctional, which makes this gene an excellent candidate for gene editing.

In new mouse models of the disease ... To fix the dysferlin mutation, Escobar uses CRISPR-Cas9, which is often described as "gene-editing scissors" and for which a Nobel Prize was awarded in ...

CRISPR-Cas9 enzymes can be used to edit genes ... The researchers conducted proof-of-concept experiments in human cells and a mouse model of retinitis pigmentosa, finding that the bespoke enzymes ...

they became the first to use CRISPR to precisely cut genes in mouse cancer cells. But this is the first time they've applied CRISPR to head and neck cancer. According to Pia and his colleagues ...