这项研究颠覆了“PAM 越宽松越好”的传统认知，揭示特异性与效率的精准平衡才是关键。 CRISPR-Cas9 被誉为“基因魔剪”，但其编辑效率在不同场景 ...

We came across a bullish thesis on CRISPR Therapeutics AG (CRSP) on Two Natural Cap’s Substack. In this article, we will ...

Using a modified CRISPR-based mechanism, the team led by Prof. Pallob Kundu has developed a stress-activated gene switch that empowers plants to survive extreme heat and microbial attacks.

Repositioning genes awakens fetal hemoglobin to treat disease. CRISPR editing may change future gene therapy. Researchers ...

The clustered regularly interspaced short palindromic repeat (CRISPR) genome-editing revolution established the beginning of a new era in life sciences. I will report the role of state-of-the-art ...

CRISPR/Cas9 is a gene editing tool that has revolutionized biomedical research and led to the first FDA-approved CRISPR-based gene therapy. However, until now, the precise mechanism of exactly how ...

CRISPR/Cas9 is a gene editing tool that has revolutionized biomedical research and led to the first FDA-approved CRISPR-based gene therapy. However, until now, the precise mechanism of exactly how ...

Innovation in biotechnology has reached new heights with the advancement of microbial genome editing services. These services enable researchers and industries to modify the genetic makeup of ...

CRISPR-Cas9, for instance, is type II, using the enzyme Cas9 as the DNA scissors. For the current investigation, the researchers examined a type III system known as CRISPR-Cas10.

This first-in-the-world approach harnesses autophagy to shift DNA repair toward homologous recombination, boosting precision editing efficiency up to threefold.