在生命的微观世界里,辅酶 A(Coenzyme A,CoA)就像一把神奇的钥匙,参与着众多重要的生物过程。它不仅在脂质代谢中发挥关键作用,还肩负着调节线粒体功能、参与膜塑形等重任。一旦 CoA 出现缺乏,就如同机器的关键零件损坏,会引发一系列严重的人类疾病 ...
The CV benefit of statins can be partly explained by their ability to inhibit of HMG-CoA reductase ... pathway decreases the formation of coenzyme Q10 (CoQ10) within the body.
Two promising strategies focus on inhibiting coenzyme A (CoA) biosynthesis and targeting essential bacterial pathways. Join Tanya Parish of the University of Washington School of Medicine and Seattle ...