Figure 1: Homologues of cellular cyclins encoded by the viruses KSHV (KS) and γMH68 (γ68) bind to one or more cellular cyclin-dependent kinases (CDKs) and phosphorylate an increased number of ...

Cyclin-dependent kinases (CDKs) are protein kinases involved in critical cellular processes, such as cell cycle or transcription, whose activity requires association with specific cyclin subunits.

Cyclin-dependent kinase enzymes (CDKs) are of two types: cell cycle-regulating CDKs that participate in the progression of the cell cycle and transcriptional ones that control gene expression.