The CD95 protein delivers crucial signals for lymphocyte death, and may also negatively regulate T-lymphocyte activation by preventing the influx of calcium ions from the cell’s exterior.
CFSE-labeled (Molecular Probes, Eugene, Oregon) cloned T cells were induced into apoptosis by exposure to anti-CD95 for 4 h. Apoptotic cells were positively purified by annexin-V–conjugated ...
A new clinical study shows that an inhibitor of Fas ligand (FasL), also called CD95 ligand (CD95L ... role of FasL is to keep cells of the immune system, so called T lymphocytes, short T cells ...