董晨教授团队在 Nature Communications 期刊发表了题为：TRIM28 is an essential regulator of three-dimensional chromatin state underpinning CD8 + T cell activation 的研究论文。

Activation and antitumor immunity of CD8+ T cells are supported by the glucose transporter GLUT10 and disrupted by lactic acid 的研究论文。 该研究发现，葡萄糖转运体10（GLUT10 ...

体外结合实验证实其可特异性识别hCA-9阳性肿瘤细胞及CD8 + T细胞/NK细胞。 "MINP-mediated 4-1BB and CD27 clustering enhances CD8 + Tcell and NK cell activation in vitro"发现MINPs锚定的激动性抗体可通过交联TNF受体家族成员4-1BB和CD27，使CD8 + ...

In a recent study, Dr. Jennifer Lund, a professor in the Vaccine and Infectious Disease Division, and her team demonstrated that bystander-activation of memory CD8 T cells during Herpes Virus 2 (HSV-2 ...

Study: GZMK-expressing CD8+ T cells promote recurrent airway ... may also facilitate the recruitment of myeloid cells, thereby leading to activation of type 2 effectors. High GZMK levels were ...

Cytotoxic or CD8 + T-cells, known for their ability to kill infected and cancer cells, require activation and differentiation within specialized niches of the tumor microenvironment to effectively ...

Researchers have found that antigen-specific killer T cells (CD8+ T cells) rapidly expand in the lungs when primed by antigen-presenting lung-resident alveolar macrophages (AMs). This interaction ...

In response, the T cells activate and make copies of themselves ... A variant form of LGL leukemia involves a specific T cell called CD8+. CD8+ T cells are T cells that carry the co-receptor ...

They recognize pathogens and secrete cytokines that activate other immune cells, including CD8+ T cells. However, they have no direct involvement in attacking and neutralizing pathogens.

It could also go both ways, he said. While Halters is still piecing together the mechanisms underlying these effects, he thinks something about the activation of the brain endothelium in ApoE4 ...

Initial data demonstrate a highly differentiated clinical pharmacodynamic profile with unprecedented levels of selective CD8+ T cell activation as well as initial evidence of anti-tumor effect ...