The decrease in CD4 cells during HIV infection seems to be driven by immune activation, which does not always correlate with viral load. Experienced clinicians are all too familiar with the ...

Researchers investigating the role of the protein CD44 in obesity and metabolic health found that CD44-deficient mice stayed lean even on a high-fat diet, while the control mice developed obesity.

Blocking a protein called CD44 has been shown to protect against obesity in mice on a high-fat diet, specifically by suppressing the formation of white fat cells.