T cell activation requires a T cell receptor (TCR) to recognize its cognate peptide in the context of an MHC molecule. In addition, the association of CD3 with the TCR–peptide–MHC complex ...

When naive T cells encounter antigen-presenting cells (APCs), membrane and cytoplasmic molecules rearrange at the T cell–APC contact area to form the immune synapse. Finetti et al. now reveal an ...

CD3 T-cell engagers have the potential to be a cornerstone of cancer treatment. They guide the immune system to find and eliminate cancer cells by binding tumor targets and the CD3 protein on ...

Details on AbCellera's poster presentation at AACR are as follows: Title: PSMA x CD3 T-cell engagers show preclinical efficacy for the treatment of prostate cancer Abstract Number: 6012 Session ...