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Macrophages elicit separate pathways for inflammation and lysosomal function in diseases due to toxic particle exposure
Human exposure to toxic particles drives various diseases. Examples include gout, an acute arthritis driven by monosodium ...
News Medical1y
SARS-CoV-2 spike protein's role in lung injury unraveled: promising new approach uncovered - News-Medical.net
The researchers evaluated the effects of daily injection of a C3a receptor antagonist (C3aRa), SB290157, beginning eight hours after the SARS-CoV-2 S1 infusion in hACE2-expressing animals to ...
Science Daily10mon
Macrophage mix helps determine rate and fate of fatty liver disease
Lipid-associated macrophages’ promotion of fibrosis resolution during MASH regression requires TREM2. Proceedings of the National Academy of Sciences , 2024; 121 (35) DOI: 10.1073/pnas ...
EurekAlert!5mon
Lrrk2 promotes M1 macrophage polarization via regulating cytokine (IFN-γ) and TLR4 (LPS)-mediated responses | EurekAlert!
This study unveiled the role of Lrrk2 gene in regulating macrophage polarization and immune response. This finding provides significant insights into the role of Lrrk2 in M1 macrophage modulation ...
The University of Alabama at Birmingham1d
In diseases due to exposure to toxic particles like gout, macrophages elicit separate pathways for inflammation and lysosomal function
In diseases due to exposure to toxic particles like gout, macrophages elicit separate pathways for inflammation and lysosomal ...