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Click-iT检测避免了BrdU检测所需的苛刻处理条件,可避免DNA变性,维持样本的形态,因而提供了一种更可靠且更简单的方法。 早期测定活性DNA的合成需要在其中掺入放射性的[3H]胸腺嘧啶脱氧核苷。后来这种方法逐渐被非放射性的核苷类似物溴脱氧尿苷(BrdU ...
在气候变化背景下,研究人员开展 BrdU - 免疫捕获结合扩增子测序研究,可检测微生物群落变化。 在气候变化的时代,研究外源性且可能具有生态毒理学影响的因素对微生物群落的作用变得愈发重要。传统的生态毒理学方法在陆地微生物群落分析方面存在局限性。
图1 研究成果(图源:Nature Medicine) 在此项研究中,研究人员通过采集5名生前接受BrdU(Bromodeoxyuridine)静脉注射的成年遗体捐献者的大脑样本 ...
To address the possibility that the HSCs in the above experiments might have continued to divide symmetrically after BrdU was discontinued, we also administered BrdU to mice from 20 to 29 days ...
BrdU in single stranded DNA, free BrdU or BrdU coupled to protein carrier. S-phase of the cell cycle. Proliferation marker. Weak cross with chloro deoxyuridine but not thymidine ...
Cell proliferation is an important indicator of cell health. It can be detected in a variety of ways, including the measurement of DNA synthesis by the incorporation of BrdU into newly synthesized DNA ...