Figure 1: Inhibition of bone formation by osteoclast-derived Sema4D. Figure 2: Plexin-B1 functions as a receptor for Sema4D in osteoblasts. Figure 3: Inhibition of bone formation by the Sema4D ...

They imitated bone formation in embryos and children, which uses cartilage as a template. This new approach appears to be a promising way of repairing bone defects. Previous attempts to create ...

The team demonstrated improved bone formation in vivo using implants with micropillars topography that induces cell nuclei deformation and facilitates the differentiation of marrow-derived stem cells ...

This bone remodeling consists of bone resorption by osteoclasts and bone formation by osteoblasts. A failure in the delicate balance between these two processes leads to pathologies such as ...

These changes promote bone formation, increasing bone density. Osteoporosis affects more than 200 million people worldwide and is a serious public health concern, according to the National ...

The monoclonal antibody romosozumab binds to sclerostin and increases bone formation. In a phase 2, multicenter, international, randomized, placebo-controlled, parallel-group, eight-group study ...

A research group has found that altering levels of a protein disrupts the balance between formation of bone and fat tissue in animal models. The results show that the protein, named Thy-1 ...

Scientists from Eindhoven University of Technology (TU/e), assisted by colleagues from the University of Illinois, have successfully mimicked the process of bone formation in the laboratory.