The gold standard technology that scientists use to detect DNA methylation is bisulfite genomic sequencing. It is a qualitative, quantitative, and efficient approach to identify methylated cytosine at ...

Pairing bisulfite conversion of the human genome with targeted enrichment and high-throughput sequencing allows a quantitative assessment of DNA methylation at base-pair resolution. A DNA molecule ...

This article explores 6-base genome sequencing and how it is empowering researchers to expand their studies to include both ...

TAPS enables direct and high-fidelity methylation mapping with significantly reduced template damage and noise compared to conventional bisulfite sequencing, unlocking new possibilities for ...

For more information, please visit the 10X website. Chromatin immunoprecipitation sequencing allows for genome-wide profiling of protein-DNA interactions and of histone PTMs. GARP offers ChIP-seq ...

Using machine learning algorithms and deep whole-genome bisulfite sequencing on freshly isolated and purified cell populations, the study unveils a detailed landscape of genetic and epigenetic ...

In their study published in the journal Science Advances, the group analyzed whole-genome bisulfite sequencing data obtained through other research efforts and conducted experiments in their lab ...

The new system includes all-in-one reagents for sample conversion, library creation and indexing, combined with bioinformatic tools to enable accurate DNA modification analysis, designed to reduce ...