In the course of evaluating the optimal duration of bisphosphonate treatment the FDA found little benefit of treatment beyond 5 years. [1,2] Moreover, examination of studies where bisphosphonates ...

Thus, patients continue to be exposed to the pharmacologic effects of bisphosphonate activity long after they stop taking the medication. The long-term safety and efficacy of bisphosphonate ...

Studies show conflicting results regarding the possible excess risk of atypical fractures of the femoral shaft associated with bisphosphonate use. In Sweden, 12,777 women 55 years of age or older ...

Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window About a year was determined to be the minimal timing of bisphosphonate therapy for postmenopausal women with ...

Many of you have likely had the experience of being contacted by a dentist who is reluctant to do a needed dental procedure for a patient taking a bisphosphonate because of concern about MRONJ.

Long-term bisphosphonate therapy can change bones at the microscopic level to make them more susceptible to the rare catastrophic transverse breaks known as atypical femoral fractures (AFFs ...

Despite potential side effects, bisphosphonate therapy may benefit postmenopausal women with osteoporosis by preventing fractures, according to a study published in JAMA Internal Medicine.

Those bisphosphonate medications can help strengthen brittle bones, but after several years of taking them, the drugs can paradoxically also lead to fractures. One strategy recommended by ...

Back to Healio The human monoclonal antibody denosumab more effectively increases bone mass in patients with low bone mineral density or osteoporosis when compared against any bisphosphonate ...

In the general analysis, patients under bisphosphonate therapy showed an increased risk for serious adverse events; however, heterogeneity was evident on pooling these data and it was, therefore ...

Researchers suggest bisphosphonate could potentially reduce the risk of colorectal cancer, but more randomized trials should be carried out to confirm their results, according to an Internal Medicine ...