It was initially thought that siRNA could escape from the interferon response, whereas long dsRNAs of >30 bp could not. However, it was shown that the siRNA also induces the interferon response 75,76.

Nature Chemical Biology - An siRNA screen for genes that suppress mutant huntingtin toxicity in both mammalian cells and Drosophila identifies glutaminyl cyclase (QPCT).

Nano Nanot biology & Med：白血病药物疗法新突破：“纳米钻石”进行药物运输克服药物耐性. 新加坡国立大学等处的研究者通过将常见的白血病多种药物 ...

文章报道了新型肝脏血管紧张素原靶向siRNA候选药物的临床前开发过程——经生物信息学筛选、化学修饰优化及结合肝脏靶向配体，成功开发出了数 ...

This improvement in siRNA stability is superior to that observed for other chemical modifications ... Scaling 3D biology: Automation, imaging, and the future of high-throughput research.

siRNA production is catalyzed by an enzyme known as the Dicer enzyme. ... Scaling 3D biology: Automation, imaging, and the future of high-throughput research. Oksana Sirenko.

Small interfering RNA (siRNA) drugs are a class of therapeutic agents that silence specific genes associated with inherited diseases. However, siRNA drugs have challenges because siRNAs often ...

Human siRNA Pool provides a tool that allows researchers examining these molecules to quickly search for siRNA pools targeting hundreds of different human genes.

Nucleic acid–based therapeutics, like small interfering RNA (siRNA), could be instrumental in treating diseases that are considered to be “untreatable” by small molecule drugs. The ...

Green tea compound helps siRNA slip inside cells Date: September 19, 2018 Source: American Chemical Society Summary: Drinking green tea has been linked to health benefits ranging from ...

SYDNEY, March 27, 2025--Novotech, a top global clinical trial provider, partners with biotech and pharma to speed siRNA therapeutic development.

After raising $33 million back in April, Shanghai-based Rona Therapeutics is using some of that money to acquire a small interfering RNA (siRNA) platform and four preclinical candidates from Sanofi.