UB researchers have uncovered how heat causes a critical receptor protein within cells to unfold and relay pain.

PR+ breast cancer responds well to hormone therapy, underscoring the need for molecular insight and targeted treatment strategies.

This module will consider the general properties of receptors, signal transduction pathway, and the regulation of their activity. Emphasis will be given to G-protein coupled receptors, receptor ...

Bio-conjugation techniques utilizing proteins, such as attaching fluorescent markers to identify cancer cells, are actively ...

Because of the variability of the biological material and the pharmacological compounds acting on G i - or G s-coupled receptors, a selection of cAMP assay kits is necessary to cover a broad range ...

the subsequent increased prevalence of cells with receptors that match similar three-dimensional structures provides a biological fingerprint of what diseases or conditions the immune system has ...

The study reveals that upon binding to harmful substances, these receptors activate efflux pumps to remove them from cells, highlighting a novel biological defense system in the skin. This finding ...

PARP7 is a mono-ADP-ribosyl transferase (mono-ART) which has recently gained attention due to its emerging role as a negative ...